PTFE ultrafiltration membrane has a minimum molecular weight cutoff of 500 Daltons and can be used to separate proteins, enzymes, nucleic acids, polysaccharides, polypeptides, antibiotics, viruses, etc. in biopharmaceuticals.
The advantages of ultrafiltration are that there is no phase transfer, no need to add any strong chemicals, it can be operated at low temperatures, the filtration rate is fast, and it is easy to perform aseptic processing.
All of these can simplify the separation operation and avoid the loss of activity and denaturation of biologically active substances.
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